Authorization according to Good Manufacturing Practice rules ISO 9001 Certification

  1. Physical, Physicochemical, and Chemical Methods

1.1. Physical Methods

  • Refractive index
  • Boiling point
  • Melting point
  • Dropping point
  • Solidification point
  • Viscosity
  • Relative density
  • Rotatory power
  • Alcohol concentration determination
  • Conductivity determination
  • Electrophoresis
  • Tonicity

1.2. Physicochemical Methods

  • Solubility
  • Appearance and color of solutions
  • Loss by drying
  • Residue on ignition
  • pH determination
  • Water determination
  • Potentiometric titration
  • Total organic carbon content
  • Phenol content determination

1.3. Chemical Methods

Indicators:

  • Acidity index
  • Ester index
  • Hydroxyl index
  • Peroxide index
  • Saponification index
  • Unsaponifiable substances
  • Control limits for inorganic impurities
  • Control limits for easily carbonizable organic substances
  • Dosage of methoxy group
  • Dosage of nitrogen in organic compounds
  • Mineralization of halogenated organic bonds and sulfides
  1. Instrumental Methods

2.1. Spectrophotometry

  • Ultraviolet and visible spectrophotometry
  • Infrared spectrophotometry
  • Atomic absorption spectrophotometry
  • Inductively coupled plasma optical emission spectrometry
  • Inductively coupled plasma mass spectrometry

2.2. Chromatography

  • Thin-layer chromatography
  • Gas chromatography
  • High-pressure liquid chromatography
  • Nitrosamines determination
  1. Pharmaceutical Methods
  • Disintegration
  • Dissolution
  • Powder particle size determination
  • Sub-visible particle determination
  • Visible particle determination
  1. Pharmacognostic Methods
  • Determination of soluble substances from plant products
  • Tannin determination from plant products
  • Volatile oil determination from plant products
  • Polyholoside determination from plant products
  • Carotene and fat-soluble vitamins determination from plant products
  • Fatty acids determination from plant products
  • Determination of plant product contamination with organochlorine and organophosphorus pesticide residues
  1. Biological and Microbiological Methods
  • Sterility control
  • Microbial contamination
  • Microbial preservative efficacy control
  • Antibiotic microbiological activity
  • Bacterial endotoxin determination
  • Sodium heparin determination
  • Mutagenic potential testing, by identifying phenotypes caused by reverse genetic mutations in bacteria (Ames test)

Drug Stability Testing

  • Long-term conditions
  • Accelerated conditions
  • Photostability
  1. Methodology Development and Validation
  2. Analytical Validation and Transfer

In accordance with Good Clinical Practice ISO 9001 Certification

1. Skin Tolerance Studies for Cosmetic Products:

  • irritant potential,
  • sensitizing potential,
  • allergic potential

2. Efficacy Studies for Cosmetic Products – Identifying Product Effect and Demonstrating Declared Effect:

  • moisturizing effect
  • regenerating effect
  • anti-ageing effect, including dermal structural protein repair (e.g., collagen)
  • anti-edematous effect
  • anti-cellulite effect
  • anti-acne effect

3. Non-invasive Instrumental Methods:

  • CORNEOMETRY
  • SEBUMETRY
  • MEXAMETRY:
    • erythema determination
    • melanin determination

CUTOMETRY – DETERMINING SKIN ELASTICITY
SELS Method (Surface Evaluation of the Living Skin) SKIN SURFACE PARAMETERS EVALUATION:

  • “Skin smoothness” (SEsm)
  • “Skin roughness” (SEr)
  • “Scaliness” (SEsc)
  • “Wrinkles” (SEw)

TRANSEPIDERMAL WATER EVAPORATION DETERMINATION
SKIN pH DETERMINATION
ULTRASONIC EVALUATIONS WITH DERMASCAN C in skin and joint tissue – with multiple applications:

  • Collagen degradation/repair in joints
  • Collagen fibers in the dermal matrix due to photo-aging and reversibility after effective treatment
  • Subcutaneous tissue thickness measurement
  • Measurement of epidermal and dermal thickness
  • Analysis of allergic and irritative reactions through edema and inflammatory infiltrates (measuring hyporeflective area dimensions)
  • Skin reactivity to allergens (e.g., patch test applications)
  • Skin atrophy due to medication (e.g., corticosteroids)

ISO 17025 Certification

List of Pesticide Residues Analyzed in the CBA Lab
Compound NameCompound NameCompound Name
GC-MS-MS Method:GC-MS-MS Method:LC-MS-MS Method:
AlaclorFlucitrinatAcefat
AldrinFludioxonilAcetamiprid
AmetrinFonofosAzoxistrobin
AtrazinFormotionBenalaxil
Azinfos-etilFosaloneBitertanol
Azinfos-metilFosmetBoscalid
BHC, AlfaHeptaclorBupirimat
BHC, BetaHeptaclor epoxidBuprofezin
BHC, deltaHexaclorobenzenCarbendazim
BHC, gammaIodofenfosCimoxanil
BifentrinMalaoxonCiproconazol
Bromofos-etilMalationCiprodinil
Bromofos-metil (Bromofos)MetacrifosDifenoconazol
BromopropilatMetidationDiflubenzuron
CiflutrinMetoxiclorDimetoat
Cihalotrin I (lambda)MevinfosDiniconazol
CipermetrinMirexEpoxiconazol
Clordan alfa-cisParaoxon-etilEtirimol
Clordan gamma-transParation (etil)Etoprofos
ClorfensonParation-metilFenhexamid
ClorfenvinfosPentacloroanilinaFlusilazol
Clorpirifos-etilPentacloroanisolFlutriafol
Clorpirifos-metilPermetrinHexaconazol
ClorprofamPiperonil butoxidHexitiazox
Clortal-dimetil (Dactal)PirazofosImazalil
DDD p,pPirimifos-etilImidacloprid
DDD o,pPirimifos-metilIsoprocarb
DDE o,pProcimidonaKresoxim-Metil
DDE p, pPrometonMecarbam
DDT o,pPrometrinMetalaxil
DDT p,pPropargitMetamidofos
DeltametrinPropazinMonocrotofos
DiazinonPropetamfosOmetoat
DiclorvosPropizamidaOxadixil
DieldrinProtiofosPenconazol
DifenilaminaQuintozenPendimentalin
DisulfotonS-421Piraclostrobin
DliclofentionSimazinPiridaben
Endosulfan peak 1SimetrinPirimetanil
Endosulfan peak 2SulfotepProfenofos
Endosulfan sulfattau-FluvalinatPropiconazol
EndrinTebufenpiradQuinalfos
EPNTecnazenRotenona
EtionTerbutilazinaTebuconazol
EtofenproxTerbutrinTetraconazol
EtrimfosTetraclorvinfosTiabendazol
FenclorfosTetradifonTiacloprid*
FenitrotionTetrasulTiametoxam
FenpropatrinTolclofos-metilTiofanat-metil
FensonTriazofosTrifloxistrobin
FensulfotionTrifluralinZoxamid*
FentionVinclozolinSpinosad *
Fenvalerat*non-accredited
Scroll to Top